Over 160 participants joined the second virtual IIS-CED conference on the 6/7th October.

Young talents in Isotope Science presented their high-level scientific results. Check out their publications

In Chem Commun, Angewandte Chemie, JACS or Nature. The conference was

framed by two plenary lectures given by Prof. Rylan Lundgren (Alberta, Canada) and Prof. Tracey Pirali (Piemont, Italy).

Scientific Programme:

Wednesday, 6th October 2021, day 1
2:00 (CET) Volker Derdau, president IIS-CED, Welcome
Session 1, Chair: Dieter Muri (F. Hoffmann-La Roche Ltd.)
Plenary Lecture:
2:10 (CET) Rylan Lundgren (University Alberta, Canada)
„Carboxylate Exchange Reactions: Mechanisms and Application in Isotopic Labeling“

3:00 (CET) Jiyao Yan (MPI für Kohleforschung, Germany)
„Tritiation of aryl thianthrenium salts with a molecular palladium catalyst“

3:20 – 3:40 (CET) Break
3:40 (CET) Joao De Oliveira (CEA Saclay & Sanofi, France)
„Direct Carbon Isotope Exchange of Pharmaceuticals via Reversible Decyanation“

4:00 (CET) Lars Kattner (Endotherm GmbH, Germany)
„Recent developments towards the synthesis of D/13C labeled vitamin D metabolites by application of
the Pauson-Khand Reaction“

4:20 (CET) Alex Talbot (CEA Saclay, France)
„Photochemical Strategy for Carbon Isotope Exchange with CO2“

4:40 (CET) Alexander Uttry (Westfälische Wilhelms-Universtität Münster, Gemany)
„Late-Stage β-C(sp3)-H Deuteration of Carboxylic Acids“
5:00 (CET) Closure day 1

Thursday 7th October 2021, day 2
Session 2, Chair: Ralf Kiesling (Boehringer Ingelheim, Germany) / Volker Derdau (Sanofi, Germany)
2:00 (CET) Sara Kopf (LIKAT Rostock, Germany)
„Selective Hydrogen Isotope Exchange with Transient Directing Groups“

2:20 (CET) Nathan Knight (University of Strathclyde, United Kingdom)
„Iridium(I)-catalysed sp3 hydrogen isotope exchange using carbonyl directing groups“

2:40 (CET) Viktor Pfeifer (Boehringer Ingelheim, Germany)
„Palladium Nanoparticles for the Deuteration and Tritiation of Benzylic Positions on Complex Molecules“

3:00 (CET) Kevin Tatoueix (CEA Saclay, France)
„Nanocatalyzed Hydrogen Isotope Exchange using batch and flow chemistries”

3:20 – 3:40 (CET) Break
3:40 (CET) J. Conor Townsley (University of Strathclyde, United Kingdom)
„Boronic Ester Mediated Hydrogen Isotope Exchanged“

Plenary Lecture:
4:00 (CET) Tracey Pirali (University Piemont, Italy)
„Precision deuteration in medchem: are we moving towards heavy drugs?“

4:50 (CET) Volker Derdau, president IIS-CED, Closing Remarks
5:00 (CET) Closure day 2